|European Rugby Champions Cup|
|Venue: Twickenham Stoop Date: Saturday, 14 October Kick-off: 17:30 BST|
|Coverage: Live on BBC Radio 5 live sports extra and updates on BBC local radio and live scores on the BBC Sport website|
Harlequins full-back Mike Brown will make his return from an ankle injury in Saturday’s Champions Cup opener against La Rochelle at the Twickenham Stoop.
The 32-year-old aggravated the complaint in the loss to Leicester on 23 September and has not played since.
Australian second-row James Horwill makes his comeback from concussion, while Ben Glynn plays at flanker in the absence of the injured Jack Clifford.
Former London Irish fly-half Ryan Lamb starts at 10 for La Rochelle.
The French side, who finished top of their domestic league last season before falling in the semi-finals of the play-offs, also include former All Black Victor Vito at number eight.
|Champions Cup opening-round coverage|
|Listen to 5 live Rugby Union Weekly’s full preview of the tournament|
|Friday 19:00 BST, 5 live sports extra & Radio Ulster:||Ulster v Wasps|
|Saturday 14:50 BST, 5 live sports extra||Racing 92 v Leicester|
|Saturday 17:15 BST, 5 live sports extra||Harlequins v La Rochelle|
|Saturday 19:30 BST, 5 live sports extra||Exeter v Glasgow|
|Sunday 15:10 BST, 5 live sports extra & Radio Wales||Toulon v Scarlets|
|Sunday 17:15 BST, 5 live sports extra||Northampton v Saracens|
|Sunday 17:30 BST, BBC Radio Wales||Ospreys v Clermont|
Harlequins are playing in Europe’s elite competition for the first time since 2014-15 and director of rugby John Kingston believes the whole club is excited.
“Saturday night will see a special atmosphere in The Stoop and all concerned can’t wait to get going,” he said.
“La Rochelle are a very impressive side and their recent record in the French domestic league speaks for itself.
Kingston is without two of his first-choice forwards with Clifford sidelined by a suspected dislocated shoulder sustained in last weekend’s win over Sale and prop Kyle Sinckler serving a seven-week ban for gouging.
However, 18-year-old Marcus Smith continues at fly-half after his impressive start to the season.
Harlequins: Mike Brown, Marland Yarde, Joe Marchant, Jamie Roberts, Tim Visser, Marcus Smith, Danny Care; Joe Marler, Dave Ward, Will Collier, Charlie Matthews, James Horwill (c), Ben Glynn, Chris Robshaw, Mat Luamanu.
Replacements: Elia Elia, Mark Lambert, Phil Swainston, George Merrick, Archie White, Dave Lewis, Tim Swiel, Francis Saili
La Rochelle: Kini Murimurivalu, Vincent Rattez, Paul Jordaan, Geoffrey Doumayrou, Jeremy Sinzelle, Ryan Lamb, Alexi Bales; Dany Priso, Hikairo Forbes, Uini Atonio, Jason Eaton (c), Jone Qovu, Kevin Gourdon, Zeno Kieft, Victor Vito
Replacements: Pierre Bourgarit, Mike Corbel, Vincent Pelo, Gregory Lamboley, Afa Amosa, Jean-Victor Goillot, Pierre Aguillon, Gabriel Lacroix